Invited Speakers

Jens Andreasen

Jens Andreasen

Ole Schwartz

Ole Schwartz

Arild Stenvik

Arild Stenvik

Björn Zachrisson

Björn Zachrisson

Dick Barendregt

Dick Barendregt

Karin Becktor

Karin Becktor

Ewa Czochrowska

Ewa Czochrowska

Nadine Houghton

Nadine Houghton

Magdalena Jaszczak-Małkowska

Magdalena Jaszczak-Małkowska

Teitur Jónsson

Teitur Jónsson

Wim Laureys

Wim Laureys

Wim Laureys

Manfred Leunisse

Manfred Leunisse

Marcel Linssen

Marcel Linssen

Marcel Linssen

Ivo Marek

Ivo Marek

Puria Parvini

Puria Parvini

Guy De Pauw

Guy De Pauw

Paweł Plakwicz

Paweł Plakwicz

Erik Reukers

Erik Reukers

^

Joerd van der Meer

Prof. Jens Ove Andreasen

Prof. Jens Ove Andreasen

DDS., Odont. Dr. H.C., Denmark

Presentation title:

Biology of successful tooth transplantation – are there any risks?

Abstract

ABiology of successful tooth transplantation – are there any risks?

Successful autotransplantation of developing teeth is dependent upon optimal healing of the periodontium and the pulp including the Hertwig’s epithelial root sheath in order to secure optimal root growth. Altogether five cellular systems become involved in post transplantation healing, and animal experiments have shown how healing complications may develop if one or more of these cellular systems are seriously damaged.

Curriculum vitae

Dr. Andreasen received his dental degree from the Royal Dental College, Copenhagen, in 1959. He did his postgraduate training in Oral and Maxillofacial Surgery at the University Hospital in Copenhagen where he now is an Associate Professor.

Dr. Andreasen has authored 372 publications and 11 textbooks, covering topics such as dental traumatology, tooth replantation and autotransplantation, tooth eruption and tooth impaction. In relation to traumatology the Textbook and Color Atlas of Traumatic Injuries to the Teeth will soon be in its 5th edition and includes 61 contributors.

He founded the interactive Dental Trauma Guide in 2008 which is now being used in 180 countries. It contains information of a series of prospective long-term studies of all types of traumatic dental injuries carried out at the Trauma Center and Department of Oral and Maxillo-Facial Surgery at the University Hospital in Copenhagen as well as information from 50 animal experiments reproducing treatment scenarios of various dental traumas affecting primary as well as permanent teeth.

Dr. Andreasen has received four honorary doctorate degrees and has been an invited lecturer in 49 countries.

Dr. Ole Schwartz

Dr. Ole Schwartz

DDS, Ph.D, Denmark

Presentation title:

Long-term survival of autotransplanted teeth

Abstract

Long-term survival of autotransplanted teeth

The optimal criterias of a successful autotransplanted tooth includes: alveolar growth and eruption in synchrony with neighbouring teeth, and the capacity of the soft tissue of the donor tooth to induce normal periodontal ligament, obliteration of the pulp, and further root formation, formation of new alveolar bone and gingiva at the recipient site, including the capacity of the grafted tooth to be moved with orthodontic forces.

During the last 30 years, numerous large clinical series of autotransplantation of teeth have been published. However these studies are using different criterias of long-term survival of tooth graft, success rates, aesthetic and patient- reported outcomes, making comparison and conclusions from the literature difficult.

All present long-term studies of autotransplantation of teeth, including Meta-analysis and Life-table analysis of several large controlled data materials (more than 4000 transplantations, followed from 3 to 47 years) have revealed a series of relevant prognostic factors of various significance on the long term “survival”. With the limitations such comparison of different data materials demand, some of the factors with potentially significant impact on long-term survival will be presented, including: Root development of the graft, tooth type, endodontic treatment, splinting, antibiotics, experience of the surgeon, in private practice vs. in university clinics, pre- and postoperative orthodontic treatment, postoperative prosthodontic treatment, and other factors of relevance to the long term satisfactory survival and function of transplanted teeth. Even cryopreserved teeth can be autotransplanted, with documented function and normal pulp and periodontal ligament for more than 30 years after autotransplantation with initial cryopreservation of the graft for 5 years.

Complications like ankylosis, necrosis of the obliterated pulp and invasive cervical resorption has been demonstrated to appear many years after tooth transplantation. It is possible to treat obliterated pulp with endodontics, however ankylosis and invasive root resorption will eventually lead to loss of the grafted tooth.

Autotransplantation of teeth present a long-term survival, function and aestetically satisfactory results after more than 20-40 years, comparable to – and in some aspects superior to – dental implants. However, transplantation of premolars to the incisor maxillary region compose a major challenge to the transplantation team, including orthodontist, surgeon and prostodontist, achieving predictable long lasting pleasing aestetic results to the patients.

Curriculum vitae

Ole Schwartz, DDS, Ph.D. Oral- and Maxillofacial Surgeon, Consultant.
Department of Oral and Maxillofacial-Surgery, University Hospital, Copenhagen, Denmark

Education

  • 1972 Certificate in Dentistry, Royal Dental College, Copenhagen, Denmark
  • 1979 Ph.D Thesis: Immunological and Clinical Aspects of Allotransplantation of Teeth in Humans
  • 1983 Certificate in Oral & Maxillofacial Surgery, Copenhagen University, Denmark

Appointments

  • 1975 Research associate, Department of Oral Surgery, University of Copenhagen, Denmark
  • 1980 Research associate, University of Los Angeles, California, USA
  • 1981 Senior research associate, University of Copenhagen, Denmark
  • 1984 Associate professor in Oral and maxillofacial surgery at University of Copenhagen
  • 1993 Head of department, Department of Oral & Maxillofacial Surgery,
    Copenhagen Community Hospitals HS, University Hospitals of Copenhagen.
  • 2000 Head of department, Department of Oral & Maxillofacial Surgery, University Hospital,
    Rigshospitalet, Copenhagen
  • 2011 Senior consultant, Department of Oral & Maxillofacial Surgery, University Hospital,
    Rigshospitalet, Copenhagen
  • 2011 Private practice part time, oral- and maxillofacial surgery, Lyngby

Awards

  • 1984 René Le Fort Award, Collegio Brazileiro Cirurgia e Traumatologica Bucco-Maxillo-Facial, Bauru, Brazil
  • 1991 SIDO World Award, Italy

Publications

73 scientific articles in peer-reviewed journals, with special focus on topics of transplantation of teeth
Chapters in textbooks:
“Atlas of replantation and transplantation of teeth”,
“Textbook and colour atlas og tooth impactions, diagnosis, treatment and prevention”,
“Textbook and colour atlas of traumatic injuries of the teeth”.

Main research focus

Tooth Autotransplantation, experimental and clinical research including cryopreservation.
Allotransplantation of Teeth, experimental and clinical research including tissue typing, immunological monitoring and and donor-specific immunosuppression.
Maxillofacial rehabilitation including bone grafting and anvanced implantology

Arild Stenvik

Arild Stenvik

Norway

Presentation title:

Transplantation and oral rehabilitation in complex cases

Abstract

Transplantation and oral rehabilitation in complex cases

At the University of Oslo Dental School we have for many years organized services for patients with complex problems by establishing interdisciplinary teams. Tooth transplantation is an important part of the treatment repertoire. The purpose of the presentation is to share some of our experiences by showing examples of various treatments carried out by the team. The conditions that will be addressed include patients with multiple teeth missing, tooth impaction, severe injuries to teeth and jaws, and ankylosed teeth. Comprehensive interdisciplinary treatment is demanding not only for the patient, but also for the professional. Good coordination and administration is necessary to ensure optimal progress of the treatment.

Curriculum vitae
  • Cand.odont. 1963, lic.odont. 1970, dr.odont. 1997, University of Oslo, Norway
  • Specialist in orthodontics, University of Oslo 1968
  • Professor and Head, Department of Orthodontics, University of Oslo 1992-2000, 2005-2010
  • Vice Dean, Faculty of Dentistry, University of Oslo 1999-2005
  • President, Norwegian Association of Orthodontists 1986-1990
  • Visiting professor ACTA, Amsterdam and Trinity College, Dublin
  • Honorary member Norwegian Association of Orthodontists
  • Honorary Doctor University of Riga
  • The Kings medal, Norway
Prof. Björn Zachrisson

Prof. Björn Zachrisson

D.D.S., M.S.D., Ph.D, Professor of Orthodontics, Norway

Presentation title:

Update on dental implants replacing missing maxillary incisors

Abstract

Update on dental implants replacing missing maxillary incisors

This lecture will discuss recent achievements in implantology, periodontology and interdisciplinary therapy which together aim to optimize the outcome of implant supported prosthetic replacements in the maxillary incisor area. Platform switching, contour augmentation, connective tissue grafts from the palate over bone grafts, ceramic abutments, and all-ceramic crowns will be covered. New evidence on the biological long-term complications of dental implants will be covered, as will the great challenges associated with predictable implant therapy regarding prevalence of peri-implant mucositis and peri-implantitis.
The long-term outcome of implant therapy will be compared with other treatment alternatives for replacement of missing anterior teeth, including space closure and transplants.

Curriculum vitae

Bjorn U. Zachrisson, Oslo, Norway

Dr. Bjorn Zachrisson is Professor Emeritus in  the Department of Orthodontics at the University of Oslo, Norway. He maintained a private orthodontic practice from 1970 to 2010. He has published more than 275 scientific and clinical articles in international journals and textbooks in orthodontics, periodontics, traumatology, and general dentistry, and presented lectures and courses world wide.

These include numerous keynote lectures and pre- or postcongress courses at International Orthodontic Congresses. He has received many awards and honors from orthodontic societies in Europe, USA, Asia, Australia, and Africa,  including the Salzmann (1986), Steiner (1990), Friel  (1997),  Mershon  (1998), Northcroft (1999), Seward (2000), and Merrifield (2000) Lectures, and the Case (1996), the OERF (Orthodontic Education and Research Foundation) (1995), the Associated Journals of Europe (1997), Burstone (1999), Kokich/Shapiro Visiting Scholar (1999), 8th SIDO World (2001), Dewel (2003,2009) and Herren (2009)) Awards. In 2007, he  received the prestigious Ketcham Award and Jarabak Award from the American Association of Orthodontists.

Dr. Zachrisson is an Honorary Member of the Orthodontic Societies of Ireland, Republic of China (Taiwan), South Africa, Israel, Poland, Serbia and Montenegro, Peru, Czech Republic, Norway and The International Tweed Foundation, as well as of the Scandinavian Academy of Esthetic Dentistry, the Interdisciplinary Dental Society of the Caribbean, the Angle Society of Europe and the European Orthodontic Society. He is Associate Editor of the Journal of Clinical Orthodontics and a Member of the Editorial Boards of  several orthodontic and dental journals.

Dr. Dick Barendregt

Dr. Dick Barendregt

DDS, MSc, PhD, Netherlands

Presentation title: (co-authors: Dr. Dick Barendregt, Dr. Manfred Leunisse, Dr. Marcel Linssen)

Trauma with loss of incisors, how to restore alveolar ridge, gingiva and tooth structure

Abstract

Trauma with loss of incisors, how to restore alveolar ridge, gingiva and tooth structure.

authors: Dr. Dick Barendregt, Dr. Manfred Leunisse, Dr. Marcel Linssen

The loss of insisors due to trauma in all cases leads to a bony and soft tissue defect of the alveolar ridge. Due to the potential of the periodontal ligament transplanted teeth offer the abiltity to restore these defects. In this lecture fully developed teeth will be transplanted to solve these defects and they will be transformed into the anatomy of incisors within six weeks after transplantation. The complete procedure will be shown.

Autotransplants as a treatment indication originally started in young patients transplanting premolars with open apices to areas with agenesis. The principle supporting the success of autotransplants as published the last 30 years, is a vital periodontal ligament. In the past 13 years, within the collaboration in Proclin Rotterdam, comparable healing was observed with autotransplants having open and closed apices. In total, up to January 1st 2018, 874 teeth were transplanted. 502 teeth had an open apex and 372 were teeth with fully formed roots. Average age for fully developed roots was 24,4 years with a range of 12-48. In 88 % of the cases, the endodontic treatment was preformed 4-6 week before transplantation. 3% of the transplanted teeth were incisors, 4% cuspids, 76% premolars and 17% molars. A total of 161 teeth were transplanted to the anterior and 211 were placed in the posterior parts of the dentition. After one year the survival rate was 99,7% (1 tooth was lost). The success rate amounted to 98,4%. In 1,3% of the cases ankylosis was diagnosed. When cases selected with a minimum observation period of 5 years 94% of the teeth survived (n=7) over an average of 7,3 years. The success percentage amounted to 91%. Compared to teeth transplanted with open apices over the same period the survival/success rates were 99% and 98% respectively (n=110).

Curriculum vitae

Dick Barendregt finished dental school in 1988 at the Rijksuniversiteit of Groningen. He worked as dentist in the Royal Dutch Navy en several private practices for a period of 5 years. In 1991 he started his Master of Science training in periodontology at the University of Amsterdam. After finishing his training in 1994 he worked as periodontist in 2 referral clinics  restricted to periodontology.

In 1996 he founded his own clinic in Rotterdam. In his clinic he works as a specialist in periodontology and implantology. The last 15 years the emphasis in patient treatment has been on the interdisciplinary planning (Proclin) together with endodontists, orthodontist, prosthetic dentist, dental technicians and oral surgeons. He is cofounder of the EndoRotterdam en PRORotterdam. Both clinics are closely related to the Clinic for Periodontology and are addresses for dentists to refer their patients to either endodontists or prosthetic/reconstructive specialists.

From 1995 to 2001 Dick Barendregt was on the board of the Dutch Society of Periodontology (NVvP) as treasurer. In this period he was the representative for the Netherlands with the EFP. After that period he joint the board of the Rotterdam Dentist Society for 10 years. Since 2009 he is member of the board of National Board on Quality of Postgraduate Dental Education.

Dick Barendregt works since 1994 with the Department of Periodontology at the University of Amsterdam and lectures in the Postgraduate Program in Periodontology. November 4th 2009 he received his PhD degree on his thesis “Probing around teeth”. He also lectures in both national and international meetings.

Dr. Karin Becktor

Dr. Karin Becktor

DDS, PhD, Denmark

Presentation Title:

The link between tooth eruption and growth of the alveolar bone

Abstract

The link between tooth eruption and growth of the alveolar bone

The first aim of the presentation is to describe the link between tooth eruption and the dentoalveolar mechanism.
The factors, which are responsible for the dentoalveolar mechanism, are not fully understood. However, it has been described that growth of the dentoalveolar bone is taking place in connection with tooth eruption, and is accordingly very dependent on a normal eruption process. Significant changes in the direction and magnitude of tooth eruption occur especially depending on the vertical development of the face.

Consequently, in growing individuals with arrested tooth eruption or loss of teeth due to trauma there will be an offset in normal dentoalveolar development, which can lead to malocclusion, malfunction and aesthetic decline.

The developmental impact that theses conditions will have on normal development, depends on three factors:

  1. The skeletal age of the patient
  2. The craniofacial growth pattern
  3. The aetiology behind the arrested tooth eruption

The second aim of this presentation is to present clinical cases treated with both implants and autotransplantation and discuss the out come in relation to the above mentioned three factors.

Curriculum vitae

Karin Binner Becktor

  • DDS: University of Copenhagen, Denmark 1990
  • Orthodontist: University of Copenhagen, Denmark 1998
  • Visiting clinician: Mayo Clinic Rochester, USA 2000
  • Beni Solow Award for best published paper in European Journal of Orthodontics 2002
  • Ph.D: University of Copenhagen, Denmark 2004
  • Active Member Angle Society of Europe 2014
  • Postgraduate course in Cranio-Mandibular function, San Sebastian Spain 2014
  • Consulting Orthodontist, University Hospital, Rigshospitalet, Copenhagen 2004-2013
  • Private practise in Hellerup, Denmark limited to orthodontics and oral surgery since 2001-
Dr. Ewa Czochrowska

Dr. Ewa Czochrowska

DDS, PhD, Poland

Presentation Title: (co-authors: Dr. Ewa Czochrowska, Dr. Magdalena Jaszczak-Małkowska)

Improving the esthetics of transplanted teeth to the anterior maxilla

Abstract

Improving the esthetics of transplanted teeth to the anterior maxilla

authors: Dr. Ewa Czochrowska, Dr. Magdalena Jaszczak-Małkowska

Traumatic loss of a maxillary incisor in growing patients is a challenging therapeutic problem, since the potential solutions must consider both adaptation due to growth adaptation and also the long term outcome In children and adolescents with missing teeth, auto transplantation of developing premolars is an attractive option as it may preserve the alveolar bone during growth and also provide predictable long-term results. Comprehensive orthodontic evaluation of many aspects of this option must be considered before treatment, including the occlusion and profile, number of missing teeth, availability of donor teeth, post-treatment stability and the patient’s expectations.

The management of anterior tooth loss with premolar transplantation is particularly challenging, because of the esthetic demands in this region. Orthodontic movement of the transplant can assist the restorative dentist in providing a restoration, which is as an ideal replacement for the missing incisor.

This presentation will discuss key issues of post-transplantation orthodontic treatment, related to the morphology of the transplant and the optimal alignment in the dental arch. Close collaboration is required between the orthodontist and the restorative dentist in order to achieve a successful outcome and individualised treatment planning is important. Clinical examples with different types of restorations will be shown to illustrate important details of this intricate procedure.

Curriculum vitae

Graduated as a dentist from the Dental Faculty in Warsaw, Poland. She finished a postgraduate training in orthodontics at the University in Oslo, Norway in 1997 then worked as a Research Fellow at the Orthodontic Department, Dental Faculty in Oslo until 2002. From 2010 she is working part-time at the Department of Orthodontics, Medical University in Warsaw and has a private orthodontic practice in Warsaw.

In 2003 she was awarded a PhD from the University in Oslo for a thesis on autotransplantation of teeth. For the publication from this work she received the American Journal of Orthodontics and Dentofacial Orthopedics Dewel Orthodontic Award in 2002. In 2014 she was awarded a habilitation in medical science from the Medical University in Warsaw on her work related to orthodontic treatment of patients with periodontitis and currently maintains a position as associate professor. Her current research is based on the outcome of tooth transplantation, tooth impaction and tooth agenesis and different aspects of interdisciplinary treatment.

Dr Czochrowska was the President of the European Orthodontic Society (2013-2015) and she host the European Confernece in 2014 in Warsaw. She is the President of the Polish Orthodontic Society (2012-2020) and the Active Member of the Angle Society of Europe and the Member of the European Board of Orthodontists.

Dr. Nadine Houghton

Dr. Nadine Houghton

BDS MDentSci, MFDS MOrth FDS(Orth), RCS(Eng), United Kingdom

Presentation title:

Leeds contribution to the scientific literature on tooth transplantation?

Abstract

Leeds contribution to the scientific literature on tooth transplantation

There is a plethora of scientific literature on tooth transplantation but there is a paucity of high quality evidence such as randomised controlled clinical trials.

This presentation will look specifically at the research carried out in The University of Leeds on the topic of tooth transplantation. The following research projects will be discussed:

  1. ‘Outcomes of tooth autotransplantation – A systematic review’ – Master of Science degree (orthodontics)
  2. Managing hypodontia using tooth autotransplantation: What is the evidence? Part of a Doctor of Philosophy degree in orthodontics
  3. Outcomes and prognostic factors that influence the success of tooth autotransplantation in children and adolescents – Master of Science degree – Paediatric dentistry (specific to a cohort of patients treated in Leeds with tooth transplants)
Curriculum vitae

Nadine started her dental career as a trainee Dental Surgery Assistant at the Birmingham Dental Hospital in 1989. She then had a change of plan and qualified as a dentist from the University of Liverpool in 1998. She did her GPT and maxillo-facial SHO posts in Liverpool over 4 years before commencing her orthodontic specialist training in Leeds. She passed her MOrth/MDentSci in 2005 and won the prestigious MOrth cases prize for her treated cases. She completed her senior orthodontic training in Birmingham and Burton upon Trent and passed her ISFE examination in 2007. Nadine has been a consultant orthodontist in Bradford/Leeds/Airedale since 2007 and her areas of interest are autotransplantation, orthognathic surgery and complex orthodontic-restorative cases.

She has an honorary senior lecturer post at The University of Leeds (UoL) and is an examiner for the Royal College of Surgeons of England. She has supervised nine research projects at UoL and has published 17 articles in the scientific literature. She is also the Northern sub-editor for the British Orthodontic Society Clinical Effectiveness Bulletin. Nadine became orthodontic Training Programme Director for Health Education England (Yorkshire and Humber –North) in October 2017.

When she is not at work, Nadine enjoys attempting to train her 3 crazy spaniels.

Dr. Magdalena Jaszczak-Małkowska

Dr. Magdalena Jaszczak-Małkowska

DDS, Poland

Presentation Title: (co-authors: Dr. Ewa Czochrowska, Dr. Magdalena Jaszczak-Małkowska)

Improving the esthetics of transplanted teeth to the anterior maxilla

Abstract

Improving the esthetics of transplanted teeth to the anterior maxilla

authors: Dr. Ewa Czochrowska, Dr. Magdalena Jaszczak-Małkowska

Traumatic loss of a maxillary incisor in growing patients is a challenging therapeutic problem, since the potential solutions must consider both adaptation due to growth adaptation and also the long term outcome In children and adolescents with missing teeth, auto transplantation of developing premolars is an attractive option as it may preserve the alveolar bone during growth and also provide predictable long-term results. Comprehensive orthodontic evaluation of many aspects of this option must be considered before treatment, including the occlusion and profile, number of missing teeth, availability of donor teeth, post-treatment stability and the patient’s expectations.

The management of anterior tooth loss with premolar transplantation is particularly challenging, because of the esthetic demands in this region. Orthodontic movement of the transplant can assist the restorative dentist in providing a restoration, which is as an ideal replacement for the missing incisor.

This presentation will discuss key issues of post-transplantation orthodontic treatment, related to the morphology of the transplant and the optimal alignment in the dental arch. Close collaboration is required between the orthodontist and the restorative dentist in order to achieve a successful outcome and individualised treatment planning is important. Clinical examples with different types of restorations will be shown to illustrate important details of this intricate procedure.

Curriculum vitae

Magdalena Jaszczak-Małkowska, DDS, specialist in prosthodontics

Graduated as a dentist from the Medical University of Warsaw, Poland in 1996. Collaborated with the Institute of Genetics and Animal Breeding of the Polish Academy of Sciences from 1996 to 1998. In 2008 she obtained a certificate as a specialist in prosthodontics. From 2016 a collaboration with the Department of Periodontology, Medical University in Warsaw on the outcome of prosthodontic treatment in patients with periodontitis. Magdalena is running a multidisciplinary private dedicated to a complex rehabilitation in adults and minimally invasive prosthodontics since 2000.

Dr. Teitur Jónsson

Dr. Teitur Jónsson

Iceland

Presentation title:(co-authors: Teitur Jónsson PhD, Hafdís Jónsdóttir DDS)

Long-term observations of transplanted premolars

Abstract

Long-term observations of transplanted premolars

authors: Teitur Jónsson PhD, Hafdís Jónsdóttir DDS
Faculty of Odontology, University of Iceland, Reykjavík, Iceland

Premolar transplants have been observed systematically since 1980 to record success, survival and complications. The long-term records of these orthodontic patients include dental and panoramic radiographs, photographs and comprehensive clinical examinations of 57 consecutive transplants. Some complications are discovered within a year from the operation, related to anatomical factors, surgical procedure and subsequent healing process. Other complications keep arising years later in the form of periapical lesions, fractured roots or crowns, lateral resorptions and caries, calling for treatment from endodontists and other dental specialists.

Curriculum vitae

Teitur Jónsson graduated from the Faculty of Odontology, University of Iceland in 1972 and finished the Postgraduate Program in Orthodontics in Oslo in1975. After that he worked in his private orthodontic practice in Akureyri, Iceland, systematically collecting transplantation records since 1980. In 2000 he became Associate Professor and later Dean of the Faculty of Odontology in Reykjavík. He was Chairman of the Scientific Committee of the 89th EOS Congress in Reykjavík in 2013 and is an Editorial Board member of the European Journal of Orthodontics.

Besides autotransplantation of teeth he has focused his research and publications on occlusal development and epidemiology, receiving his PhD from the University of Iceland for his thesis “Development of occlusal traits and space conditions. Changes from adolescence to adulthood and long-term effect of orthodontic treatment.”

Dr. Wim Laureys

Dr. Wim Laureys

DDS, PhD, Belgium

Presentation title:

Tooth transplantation, an update on cryopreservation

Abstract

Tooth transplantation, an update on cryopreservation

This lecture will focus on the different techniques and the influence of cryopreservation on the hard and soft dental tissues. Pulp regeneration after transplantation starts with revascularization and is a key process in tooth autotransplantation. The necrotic masses of the dying original pulp are a very important stimulative factor in this process. The original pulp tissue may function as a scaffold during the replacement and it may attract new cells.
Since it is difficult to cryopreserve pulp tissue inside the tooth, we tested cryopreservation and transplantation of teeth after removal of the pulp tissue at the moment of extraction.
If we remove the original pulp tissue, is revascularization of the pulp chamber after transplantation still possible?
Moreover, is there any difference between cryopreserved and directly transplanted teeth in this respect ?
Natural scaffolds such as a blood clot in the pulp chamber created during the transplantation procedure or artificial scaffolds made of biomaterials, eventually seeded with mesenchymal cells or cytokines, may enable the ingrowth of new tissue in the pulp chamber.
New developments in tissue engineering and stem cell manufacturing can help us cryopreserve teeth and restore pulp vitality after transplantation.

Curriculum vitae

Wim Laureys

Diploma

  • MSc in dentistry (DDS) : Universiy Ghent, 1993 ( cum laude/ with honor)
  • MSc. in Orthodontics : University Ghent, 1997 ( magna cum laude/ with great honor)
  • Erkend Stagemeester(internship supervisor) Orthodontics:since 2007( UGent, KULeuven)
  • Doctor in Health Sciences (PhD.), University Ghent, 2016

Position

1997-2001: teacher of post-graduate courses “Permanente Vorming Tandheelkunde”, University Ghent, Topics:

  • Trauma and agenesis
  • Obstructif sleep apnea
  • Orthodontic diagnosis and treatment planning, Part I en Part II
  • Tooth autotransplantation

1997-2015: part-time staff member department of Orthodontics, Univ.Ghent (Prof.L.Dermaut- Prof.G.De Pauw)
1997 – present: private practice in Orthodontics, Brugge. Belgium

Lectures and presentations

  • Dental malformations in cleidocranial dysplasia: morphologic appearances and therapeutic consequences. Case report – 3th Mediterranean Congress of Oral and Maxillofacial Surgery; Nice (France); 1995.
  • Revascularisation after cryopreservation and autotransplantation of immature and mature apicoectomized teeth. Poster presentation; AAO-congress, Chicago, USA; 2000.
  • 77th Congress EOS, Ghent, Belgium (2001). Revascularisation after cryopreservation and autotransplantation of immature and mature apicoectomized teeth. Oral presentation.
  • Revascularisation of autotransplanted immature and mature apicoectomized teeth: a histological study (co-author); Poster presentation 77th EOS-congress Ghent, Belgium; 2001
  • Orthod. Select: Literature review and critical analysis. Vol. 2(5); Sept. 2001.
  • European Journal of Orthodontics, Abstract 23(4); Aug. 2001.
  • COS/NVOS : invited speaker: “Cryopreservatie en tandtransplantatie”, Antwerpen, 2002.
    Studiedag Centrum voor Gehoor- en Spraakrevalidatie, UZ Gent: invited speaker: “Afwijkende mondgewoonten en gelaatsgroei”, 13/12/2002.
  • 10de septemberdag BAED (Belgian Academy of Esthetic Dentistry),invited speaker: “Autotransplantatie en cryopreservatie”. Brussel, 6/9/2003
  • 2005-2006: lectures for VVT-study clubs in Mechelen, Roeselare en Brugge: ”orthodontie en autotransplantatie”.
  • 82th EOS-congress, Vienna, Austria 2006. Oral Presentation: ”Does removal of the original pulp tissue before autotransplantation influence the ingrowth of new tissue?”
  • 86thEOS-congres, Portoroz, Slovenia, 2010. Oral Presentation “The critical apical diameter”
    COS, invited speaker:” Autologe tandtransplantatie”, Sevillia, Spain. September 2011.
  • 1st Congress on tooth transplantation, Sopot, Poland. 20-22 May, 2016. Workshop and oral presentation.

Publications

  • Onderhandelen in de spreekkamer (red. Prof. H. Lamberts, Amsterdam).Book, Chapter: “Orthodontie”, Coutinho, Bussum, Nederland; 2000.
  • Revascularisation after cryopreservation and autotransplantation of immature and mature apicoectomized teeth. Am. J. Orthod. Dentofac. Orthoped.: 2001;119(4):346-52.
  • Het Tandheelkundig Jaar 2003 : Chapter “ Cryopreservatie en autotransplantatie”; Bohn Stafleu Van Loghum; 2003.
  • Histologic analysis of pulpal revascularization of autotransplanted immature teeth after removal of the original pulp tissue. Am. J. Orthod. Dentofacial Orthop.:2004; 125(1): 93-99.
  • Does removal of the original pulp tissue before autotransplantation influence ingrowth of new tissue in the pulp chamber? Dental Traumatology: 2010; 26(5): 301-5.
  • The critical apical diameter to obtain regeneration of pulp tissue after tooth transplantation, replantation or regenerative endodontic treatment.J.Endod.: 2013; 39(6):759-63.

Awards

  • S.P.O.O.R. award 2001: “Cryopreservation and autotransplantation of teeth”.
  • BBUSO-award 2001, for the best poster at the 77th EOS congress Ghent, Belgium (co-author).
Dr. Manfred Leunisse

Dr. Manfred Leunisse

Netherlands

Presentation title: (co-authors: Dr. Dick Barendregt, Dr. Manfred Leunisse, Dr. Marcel Linssen)

Trauma with loss of incisors, how to restore alveolar ridge, gingiva and tooth structure

Abstract

Trauma with loss of incisors, how to restore alveolar ridge, gingiva and tooth structure.

authors: Dr. Dick Barendregt, Dr. Manfred Leunisse, Dr. Marcel Linssen

The loss of insisors due to trauma in all cases leads to a bony and soft tissue defect of the alveolar ridge. Due to the potential of the periodontal ligament transplanted teeth offer the abiltity to restore these defects. In this lecture fully developed teeth will be transplanted to solve these defects and they will be transformed into the anatomy of incisors within six weeks after transplantation. The complete procedure will be shown.

Autotransplants as a treatment indication originally started in young patients transplanting premolars with open apices to areas with agenesis. The principle supporting the success of autotransplants as published the last 30 years, is a vital periodontal ligament. In the past 13 years, within the collaboration in Proclin Rotterdam, comparable healing was observed with autotransplants having open and closed apices. In total, up to January 1st 2018, 874 teeth were transplanted. 502 teeth had an open apex and 372 were teeth with fully formed roots. Average age for fully developed roots was 24,4 years with a range of 12-48. In 88 % of the cases, the endodontic treatment was preformed 4-6 week before transplantation. 3% of the transplanted teeth were incisors, 4% cuspids, 76% premolars and 17% molars. A total of 161 teeth were transplanted to the anterior and 211 were placed in the posterior parts of the dentition. After one year the survival rate was 99,7% (1 tooth was lost). The success rate amounted to 98,4%. In 1,3% of the cases ankylosis was diagnosed. When cases selected with a minimum observation period of 5 years 94% of the teeth survived (n=7) over an average of 7,3 years. The success percentage amounted to 91%. Compared to teeth transplanted with open apices over the same period the survival/success rates were 99% and 98% respectively (n=110).

Curriculum vitae

Manfred Leunisse finished his dental school in 1987 at the University of Amsterdam. For one and a half year head did research at the department of orthodontics at het Free University of Amsterdam. In 1989 he started his post-graduated training at the Academic Centre for Dentistry in Amsterdam where he finished his training in January 1993. In march 1993 he founded his own orthodontic practice in Rotterdam. Besides his practice he is giving postgraduate courses for dentists.

Since 1997 the interest has shifted to patients treated in a interdisciplinary team (Proclin) together with Dick Barendregt and with prosthodontists, periodontologists, endodontologist and oral surgeons.
He also lectures in both national and international meetings.

Dr. Marcel Linssen

Dr. Marcel Linssen

Netherlands

Presentation title: (co-authors: Dr. Dick Barendregt, Dr. Manfred Leunisse, Dr. Marcel Linssen)

Trauma with loss of incisors, how to restore alveolar ridge, gingiva and tooth structure

Abstract

Trauma with loss of incisors, how to restore alveolar ridge, gingiva and tooth structure.

authors: Dr. Dick Barendregt, Dr. Manfred Leunisse, Dr. Marcel Linssen

The loss of insisors due to trauma in all cases leads to a bony and soft tissue defect of the alveolar ridge. Due to the potential of the periodontal ligament transplanted teeth offer the abiltity to restore these defects. In this lecture fully developed teeth will be transplanted to solve these defects and they will be transformed into the anatomy of incisors within six weeks after transplantation. The complete procedure will be shown.

Autotransplants as a treatment indication originally started in young patients transplanting premolars with open apices to areas with agenesis. The principle supporting the success of autotransplants as published the last 30 years, is a vital periodontal ligament. In the past 13 years, within the collaboration in Proclin Rotterdam, comparable healing was observed with autotransplants having open and closed apices. In total, up to January 1st 2018, 874 teeth were transplanted. 502 teeth had an open apex and 372 were teeth with fully formed roots. Average age for fully developed roots was 24,4 years with a range of 12-48. In 88 % of the cases, the endodontic treatment was preformed 4-6 week before transplantation. 3% of the transplanted teeth were incisors, 4% cuspids, 76% premolars and 17% molars. A total of 161 teeth were transplanted to the anterior and 211 were placed in the posterior parts of the dentition. After one year the survival rate was 99,7% (1 tooth was lost). The success rate amounted to 98,4%. In 1,3% of the cases ankylosis was diagnosed. When cases selected with a minimum observation period of 5 years 94% of the teeth survived (n=7) over an average of 7,3 years. The success percentage amounted to 91%. Compared to teeth transplanted with open apices over the same period the survival/success rates were 99% and 98% respectively (n=110).

Curriculum vitae

Marcel Linssen got his doctoral degree in dentistry at Utrecht University in 1988 and finished his Dental examinations at the Catholic University of Nijmegen in 1989. From 1991 onwards he was one of the founding fathers of a large general dental clinic in Rotterdam. From 2012 onwards he is working at PRO-Rotterdam, a reference clinic for prosthodontics and restorative dentistry, and PROCLIN, a clinic for the interdisciplinary treatment of dento-alveolar trauma, amelogenesis imperfecta, oligodontia, treatment of wear in combination with orthodontics and autotransplants.

Dr. Ivo Marek

Dr. Ivo Marek

DDS, PhD, Czechia

Presentation title:

Central incisor ankylosis in children – extraction, distraction or autotransplantation?

Abstract

Central incisor ankylosis in children – extraction, distraction or autotransplantation?

Marek I., Starosta M., Novosad M.
Dental clinic of Medical Faculty at University of Palacky, Olomouc
Private Dental Clinic STOMMA, Breclav, Czech Republic

Central incisor ankylosis in children due to injury constitutes a severe therapeutic problem. If ankylosis appears at a very early age, it leads to a gradual reinclusion. As a result there occur an aesthetic handicap and more importantly a bone loss vertically in the site of central incisor – it can constitute a severe problem for future implantation. The difference in vertical level of bone in ankylosed tooth and adjacent teeth can be 8-10 mm due to adolescent growth spurt. And this is difficult to be solved by vertical augmentation before implantation.

The authors show individual cases with differential diagnostics leading to individual solutions. The attention is aimed to distraction of a bone block with the ankylosed tooth by a fixed appliance. This unconventional solution – possible only after the end of the growth of the patient – enables restoring vertical bone level together with soft tissues in the vicinity of the tooth.

Curriculum vitae

MUDr. Ivo Marek, PhD, graduated with a degree in Dentistry from the Faculty of Medicine at Palacky University in Olomouc in 1990. He completed a three-year training program for Orthodontics in 1999 and finished his postgraduate study of Orthodontics at the Orthodontic Department of Dental School at Palacky University in Olomouc in 2007, where he earned his PhD. Dr. Marek runs his Private Dental Clinic in Breclav, where he focuses on interdisciplinary dental care. Above all, he focuses on the collaboration of orthodontists with periodontists and implantologists. Moreover, the Dental Clinic has gained credibility for several important clinical successes. For example, Marek’s clinic has the privilege of being the first clinic in the Czech Republic which has performed the autotransplantation of a premolar, etc.

Dr. Marek works as an Associate Professor at the Orthodontic Department of Dental School, Palacky University, in Olomouc, in both graduate and postgraduate study programs. In addition, he is a part-time teacher at the Orthodontic Department at Charles University’s Faculty of Medicine, in Prague.
He has published 45 articles and has given over 190 lectures in the Czech Republic and abroad.

Dr. Marek is a Vice President of the Czech Orthodontic Society, and not only a member of the European Orthodontic Society, but also the American Orthodontic Society and the World Orthodontic Society. In 2007, he was appointed Honorary Member of the Implantology Club of Czech Republic for the partnership between the fields of orthodontics and implantology. Furthermore, he is a member of the editorial board of the journal “Ortodoncie” (Orthodontics) and reviewer of the journal “Ortodoncie”, Journal of Aligner Orthodontics, The Angle Orthodontist and European Journal of Orthodontics. He is member of the accreditation committee of the Ministry of Healthcare and a representative of the Czech Orthodontic Society in EFOSA, as well as an AAO Ambassador and member of Council of European Orthodontic Society.

Dr. Puria Parvini

Dr. Puria Parvini

DDS, M.Sc.

Presentation title:

Transplantation of deciduous canines

Abstract

Transplantation of deciduous canines

Autotransplantation of deciduous canines offers a method for replacing congenitally missing teeth or traumatized maxillary incisors particularly in children. As most tooth losses due to traumatic incidents occur in young patients, implant placement is contraindicated until growth has finished. In case of a “no donor dilemma” and if a suitable deciduous canine is available, autotransplantation may be the therapy of choice.

Auto-alloplastic transplantation of primary canines is possible for children ages 8 to 11 when the children and parents are compliant. After the antiresorptive-regenerative therapy and the preparation of the tooth Titanium posts are inserted extraorally into the root canal from the retrograde direction in order to achieve an optimal crown to root ratio. The roots of the transplants are physiologically resorbed but are supposed to maintain a root length of at least 3mm.

This treatment modality is not widely known as a treatment option by dentists and oral surgeons who usually insert dental implants after cessation of growth or fixed partial dentures to substitute a missing tooth. It can also be applied, if apremolar transplantation is not possible. In case of failing or missing teeth, our patients have the opportunity to choose a procedure that can provide them with all the benefits of a natural replacement.

Curriculum vitae

Dr. Puria Parvini, M.Sc.

UNIVERSITY LEVEL EDUCATION: Johannes Gutenberg-Universität, Mainz, Faculty of Dentistry

  • WS 2003 – Staatsexamen
  • March 2006 – Dissertation for Doctor Medicinae Dentaire
    Dissertation title: Clinical evaluation of the quality of life and subjective chewing ability and nutritional intake in edentulous patients with a conventional removable denture in the upper jaw and implant supported overdentures in the lower jaw.
    Under the Auspices of: Prof. Dr. Frauke Müller, Universität Genf/Schweiz
  • 2006 – Assistant Professor – Department of Oral Surgery and Implantology. Goethe University, Frankfurt
  • 2007 – Empowerment of national audit office as auditor in the state exam
  • 2007 – Assessment of equivalence Iran (DDS)
  • 2009 – Oral Surgeon – Specialist in oral surgery & implantology
  • 2010 – Senior Physician – Department of Oral Surgery and Implantology. Goethe University, Frankfurt
  • 2010 – Accredited Tutor & Supervisor – Master of Science in Oral Implantology. Goethe University, Frankfurt.
  • 2011 – ACLS Instructor for American Heart Association (Cardiovascular Life Support Instructor)
  • 2011 – Trainer for BLS and ACLS American Heart Association
  • 2012 – Award for Excellence in Teaching. Goethe University, Frankfurt
  • 2013 – Examined Expert of Implantology of DGOI
  • 2013 – Diplomate ICOI & Fellowship ICOI
  • 2013 – Empowerment of national audit office as auditor in the assessment of equivalence, Germany/Hessen
  • 2013 – Radiation Protection Representative – Dental Clinic. Goethe University, Frankfurt
  • 2014 – Entry to the Oral Surgery Specialist List GDC, United Kingdom
  • 2014 – Speaker “Pilotprojekt Oralchirurgie.” Chamber of Dentists of the Federal State of Hessen
  • 2015 – Master of Science Parodontology and Implany Therapy, DGPARO/ DIU
  • 2015 – Chief Senior Physician and Absentee’s Representative of Clinic Director Department of Oral Surgery and Implantology Goethe University, Frankfurt
  • 2016 – Dentsply Ankylos Award – Best Surgical Film
  • 2017 – Award for Excellence in Teaching. Goethe University, Frankfurt
Dr. Guy De Pauw

Dr. Guy De Pauw

DDS, PhD, Belgium

Presentation title:

State-of-the art on tooth transplantation

Curriculum vitae

Guy De Pauw

Academic degrees

  • Dental Sciences: 1980-1985, UGent
  • Specialist in Orthodontics and Dentofacial Orthopaedics : 1985-1989, UGent
  • Specialist in Orthodontics and Dentofacial Orthopaedics: 1994, Register of Specialists, The Netherlands
  • PhD, University of Ghent: “Orthopaedic displacement of the maxilla”, October 10th, 2002
  • Postgraduate training in Hospital Management (UZGent)

Functions at the University

  • Full time staff member at the orthodontic department (organisation of department, clinical supervisor, teacher, researcher), 1989
  • Part time staff member, 1993-2006
  • Full professor and chairman of the Orthodontic Department, 2006-
  • Coordinator Centre of Congenital Facial Anomalies, 2006-
  • Dean Dental School, 2007-2011
  • Coordinator of Orthodontic Master after Master Postgraduate Programme, 2007-
  • Member of the Faculty of Medicine and Health Sciences, 2008-
  • Member of the sector council University Hospital Ghent, 2009-2011
  • Head Dental Department University Hospital Ghent, 2015-

Promotor of PhD thesis

  • 2010: PhD thesis titled “Osteopontin and bone healing” of Madjid Gordjestani” was defended on 21st of October 2010
  • 2011: PhD thesis titled “Cryopreservation and autotransplantation of teeth – An in vitro and in vivo study” of Liesbeth Temmerman was defended on 16th of December 2011
  • 2016: PhD thesis titled “Expanding the application possibilities of tooth transplantation with specific emphasis on pulp regeneration” of Laureys Wim was defended on 3rd of May 2016
Dr. Paweł Plakwicz

Dr. Paweł Plakwicz

DDS, PhD, FDSRCS (Eng), Poland

Presentation title:

Complications: diagnosis and treatment

Abstract

Complications: diagnosis and treatment

Autotransplantation of teeth is a well-established procedure for the replacement of missing or lost teeth, however not every treatment is successful. The lecture will provide information on intraoperative and postoperative complications diagnosed at the time of the surgical procedure and during healing of autotransplanted teeth. The description of potential risk factors that may influence the surgery and treatment outcomes will be given and discussed. Complications such as root resorption, pulp necrosis and root growth disturbances are detected in small percentage of patients undergoing transplantation of developing premolars. More complications can be expected with respect to other types of transplanted teeth and different treatment protocols. Problems regarding pulp necrosis and inflammatory resorption can be successfully treated in most cases but treatment of ankylosis still remains unsolved. Theese issues will be presented and addressed based on clinical experience and the literature.

Curriculum vitae

Paweł Plakwicz, DDS, PhD, FDSRCS (Eng)
Associate Professor, Dept. of Periodontology, Medical University of Warsaw, Poland

Dr Plakwicz graduated from the Dental Faculty, Medical University of Warsaw, Poland. In 2000 he completed his postgraduate training in autotransplantation of teeth at the University of Oslo, Norway. In 2001, he qualified as a specialist in Oral Surgery. Since 2009 he has worked at the Department of Periodontology, Medical University of Warsaw. In 2009 he defended his PhD thesis on autotransplantation of teeth and in 2015 he gained his PhD with habilitation for series of publication under the title: “Periodontal assessment of the treatment outcomes of autotransplantation of developing teeth in growing patients”. He performed and followed more than 350 of autotransplantated teeth. His main research interests are in the treatment of growing patients with missing teeth and disturbances of eruption and the bone growth that follows the autotransplantation of the teeth.

Dr. Erik Reukers

Dr. Erik Reukers

Netherlands

Presentation title:

Thinking out of the box using autotransplants

Curriculum vitae

Erik Reukers graduated from the Faculty of Dentistry, University of Nijmegen in 1985. After working as a dentist for 6 years he finished the Postgraduate Program in Orthodontics in Nijmegen in 1995.

He wrote a PhD thesis called “Straight wire appliance versus conventional full edgewise: a prospective clinical trial” in 1997. After that he worked in his private orthodontic practice, first in Zutphen and later in Nijmegen and was responsible for the post academic orthodontic program for dentists at the University of Nijmegen.

Currently he is examiner for the Dutch dental specialists registration commission. He gives lectures for dentists and writes articles about various orthodontic topics for a Dutch dental journal.